Using molecules to detune nanodrums

The analysis of the minutest quantities of pharmaceutical samples is of crucial importance for the research and synthesis of new medications. At the moment it represents a technical challenge, but a new infrared method of measurement developed by TU Wien in collaboration with two research groups from Copenhagen may remedy this. (above) Microscope image of a filter membrane with gold electrodes to detect the mechanical vibrations. (below) Microscope images of the filter membrane before and after the sampling of a chemical specimen. Materials for pharmaceutical products are an expensive commodity, meaning appropriate caution is called for when it comes to synthesising new medications, for example. A precise measuring instrument is required in order to test or adapt the desired composition. A common measurement method to date has been infrared spectroscopy.