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A joint study by MedUni Vienna and Stanford University has investigated the relationship between the stress hormone cortisol and the size of the hippocampus in different types of depression. It was found that patients with psychotic depression have higher cortisol levels in the evening, while in non-psychotic depression, higher nocturnal cortisol levels are associated with a smaller hippocampus.

Recently published analyses led by Josef Smolen of MedUni Vienna provide new insights into how certain blood values can influence the effectiveness of medications for rheumatoid arthritis (RA). The results are based on an evaluation of the large-scale international EXXELERATE study and a supplementary investigation that offers further insights into the role of rheumatoid factor and other biomarkers.

Cutaneous T-cell lymphoma is a rare form of blood cancer, the advanced stages of which are associated with a poor prognosis. A new study by MedUni Vienna, Charité - Universitätsmedizin Berlin and the Max Delbrück Center has identified the protein CD74 as a promising target for innovative treatments.

A study led by the Medical University of Vienna has for the first time investigated the frequency of new persistent opioid use after surgery in Austria. The results show that 1.7% of patients continue to take opioids for at least three to six months after surgery, i.e. beyond a period when acute postoperative pain has usually subsided.

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting around 250,000 people in Austria. While previous treatment approaches have mainly focused on inhibiting pro-inflammatory immune cells, a study led by MedUni Vienna shows that it is possible to restore the function of certain anti-inflammatory immune cells in a targeted manner.

A recent study involving the Medical University of Vienna in an international collaboration provides new insights into bacterial vaginosis, the most common infection of the female genital tract caused by bacteria. This disease is associated with an increased risk of sexually transmitted infections, HIV and premature births.

Monocytes, the sentinel cells of the innate immune system, form the first line of defence against viral infections. A team of researchers from MedUni Vienna has now discovered a previously unknown mechanism that enables these cells to fight SARS-COV-2. The study results, recently published in the journal "Frontiers in Immunology", open up new possibilities for the treatment of particularly severe cases of COVID-19.

Generative artificial intelligence (AI) enables the creation of large, anonymized image datasets for the development of diagnostic systems. As part of an international collaboration, researchers at MedUni Vienna have developed a generative AI that can generate and process synthetic medical imaging data.

An interdisciplinary research team led by the Department of Pediatrics and Adolescent Medicine and the Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital has investigated the potential of liquid biopsies from blood and cerebrospinal fluid for the diagnosis and monitoring of brain tumors in children and adolescents.

A research team from the University of Vienna and the Medical University of Vienna is breaking new ground in precision medicine: it has developed an innovative method for analyzing metabolic profiles from finger sweat. The results of a pilot study just published in the renowned EPMA Journal show that this non-invasive method can be used in breast cancer patients to obtain information about the course of the disease, the effects of therapy and individual lifestyle habits.

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face. Locally advanced tumours in particular can be difficult to treat surgically. A research team from MedUni Vienna and University Hospital Vienna has now investigated the effectiveness of a new type of therapy and achieved promising results: The active substance TVEC led to a reduction in the size of the basal cell carcinoma in all study participants, which not only improved surgical removal, but also led to a complete regression of the tumour in some of the patients.

In a paper recently published in the leading journal "The Lancet Digital Health", a scientific team led by Stanisa Raspopovic from MedUni Vienna looks at the progress and challenges in the research and development of brain implants. New achievements in the field of this technology are seen as a source of hope for many patients with neurological disorders and have been making headlines recently.

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod. This combination showed promising results in topically accessible tumors like melanoma and breast cancer models: The therapy led to the death of tumor cells at the treated sites and simultaneously activated the adaptive immune system to fight even distant metastases.

Researchers at MedUni Vienna have joined forces with the Viennese start-up TAmiRNA to develop a test that aims to improve the safety of liver surgery. The invention by Alice Assinger and Patrick Starlinger is based on the precise analysis of circulating microRNAs and is now ready for the market. Postoperative liver failure remains the most common cause of death after liver resection.

Researchers at CeMM and the Medical University of Vienna have developed an innovative microscopy-based approach that could predict the best approved drug to treat individual rheumatoid arthritis patients using samples of their blood. Published in the Lancet group journal EBioMedicine the study demonstrates the feasibility of precision medicine to significantly enhance treatments for rheumatoid arthritis and likely other autoimmune diseases.

An innovative study by the Karl Landsteiner University of Health Sciences (KL Krems) and the Medical University of Vienna (MedUni Vienna) provides new insights into the genetic mechanisms of birch pollen allergy. The research team observed significantly more active genes for immunological signalling pathways in the nasal mucosa of allergy sufferers after exposure to birch pollen than in unaffected individuals.

A study by the Medical University of Vienna investigated the development of utilisation of various levels of the Austrian healthcare system between 2006 and 2019. By analysing three population surveys conducted by Statistics Austria, it was found that all'healthcare facilities have a rising number of patient visits.

A research team from the Medical University of Vienna, the University of Vienna and the Yale School of Public Health has analysed the way breastfeeding and commercial milk formula are presented in more than 2,500 articles in Austrian print and online media over a period of two decades (2002-2022).

A recent study led by MedUni Vienna provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains special vesicles that trigger rapid coagulation of the blood of haemophilic patients.

Researchers from the Vienna Lung Transplant Program of MedUni Vienna and University Hospital Vienna have published the first prospective, randomized and controlled study on the use of extracorporeal photopheresis (ECP) in lung transplantation in the renowned European Respiratory Journal. The findings could significantly change the standard procedure for rejection reactions after lung transplants.