news 2020

Researchers from TU Graz, Med Uni Graz and Uni Graz are working on a digital interactive information system that automatically tailors medical content to individuals and their needs. Additional Images for download at the end of the text Can this digital medium make predictions about the individual information needs of users, recognize their cognitive abilities, and use this data to convey high-quality medical content in a comprehensible and clear manner?

By Christoph Pelzl Researchers from TU Graz, Med Uni Graz and Uni Graz are working on a digital interactive information system that automatically tailors medical content to individuals and their needs. Additional Images for download at the end of the text Can this digital medium make predictions about the individual information needs of users, recognize their cognitive abilities, and use this data to convey high-quality medical content in a comprehensible and clear manner?

By Susanne Eigner Researchers from TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of nucleic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest.

High-resolution mass spectrometry promotes new methods for analysis Humans are exposed to various environmental or dietary molecules that can attenuate or even increase the effect of therapeutic drugs. Studies on the industrial chemical bisphenol A and the phytoestrogen genistein, for example, have shown drug-exposome interactions.

By Christoph Pelzl The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases. The renin-angiotensin system (RAS) becomes active at low blood pressure and forms angiotensin II, a hormone that causes blood vessels to constrict, causing blood pressure to rise again.

In order to analyze tumors, they have to be cut into thin slices. Now, a new technology has been developed that makes pieces of the tumor visible in 3D without cutting them. After cancer surgery, the crucial question is: Are there possibly cancer cells left behind that can continue to grow, or has the entire tumor actually been removed? To find out, the tumor is examined by pathologists.

Decades-old data is being used to describe the propagation of tiny droplets. Now a fluid dynamics team has developed new models: Masks and distancing are good, but not enough. 1/2 images Droplets with a viral load [Translate to English:] Tröpfchen haben begrenzte Reichweite, Aeorsole können aber größere Distanzen überbrücken [Translate to English:] Tröpfchen haben begrenzte Reichweite, Aeorsole können aber größere Distanzen überbrücken Wear a mask, keep your distance, avoid crowds - these are the common recommendations to contain the COVID-19 epidemic.

Ein ForscherInnen-Team um Sigurd Lax, Professor für Pathologie an der Johannes Kepler Universität Linz und Vorstand des Instituts für Pathologie des Landeskrankenhauses Graz II hat gemeinsam mit Kollegen der Medizinischen Universität Graz und der Medizinischen Universität Wien eine Studie zur postmortalen Virendynamik von SARS-CoV-2 veröffentlicht.

By Christoph Pelzl Joint investigations by researchers from Graz University of Technology and the ÖAMTC show that the risk of serious head injuries increases when an already damaged helmet or a wrong helmet is worn. Additional can be found at the end of the message In Austria, more than 4,100 moped riders are injured in road accidents every year - including many young people.

Postgenomic technologies reveal new mechanism of stress-induced chemoresistance Resistance of cancer cells against therapeutic agents is a major cause of treatment failure, especially in recurrent diseases. An international team around the biochemists Robert Ahrends from the University of Vienna and Jan Medenbach from the University of Regensburg identified a novel mechanism of chemoresistance which has now been published in "Nature Communications".

By Christoph Pelzl Researchers from Graz, Austria, are developing a ground-breaking method that uses biomarkers to detect sepsis 2 to 3 days before the first clinical symptoms appear. This can significantly increase the chances of survival in cases of blood poisoning by bacteria or fungi. Additional at the end of the text Whether activating or silencing genes, breaking down defective cells or building new tissue, our body is constantly working to repair itself, even in cases of illness.

Researchers discover a novel checkpoint in immune cells with the potential to treat the cancer cell microenvironment The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.