news 2024

A MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases. In an experimental study, pharmacological inhibition of an enzyme that plays a central role in fat metabolism promoted liver health reduced liver fat, inflammation and fibrotic remodeling (connective tissue scarring).

Diffuse hemispheric glioma (DHG) is a brain tumor in children, adolescents and young adults with an average survival prognosis of less than two years and limited treatment options. A research team from MedUni Vienna and University Hospital Vienna has identified increased stress through targeted DNA breaks with simultaneous inhibition of DNA repair in the tumor cell as a promising therapeutic approach.

The transition to low-emission technologies such as electric vehicles and photovoltaic systems is central to climate protection and also brings major benefits for public health, e.g. through less air pollution. However, these technological solutions use materials such as so-called technologically critical elements (TCEs), some of which are potentially harmful to the environment and human health.

The Ignaz Semmelweis Institute will start work at the beginning of 2025.

The black box of the human brain is beginning to open. Although animal models are crucial for our understanding of the mammalian brain, the less frequently collected human data reveal important peculiarities. In a recent paper published in the journal Cell, a team led by the Institute of Science and Technology Austria (ISTA) and the Medical University of Vienna has shed light on the human hippocampal region CA3, which is central to memory storage.

The black box of the human brain is beginning to open. Although animal models are crucial for our understanding of the mammalian brain, the less frequently collected human data reveal important peculiarities. In a recent paper published in the journal Cell, a team led by the Institute of Science and Technology Austria (ISTA) and the Medical University of Vienna has shed light on the human hippocampal region CA3, which is central to memory storage.

ISTA biologists team up with neurosurgeons to unravel the human brain's specificities The black box of the human brain is starting to crack open. Although animal models are instrumental in shaping our understanding of the mammalian brain, scarce human data is uncovering important specificities. In a paper published in Cell , a team led by the Jonas group at the Institute of Science and Technology Austria (ISTA) and neurosurgeons from the Medical University of Vienna shed light on the human hippocampal CA3 region, central for memory storage.

As much as targeted therapy using so-called EGFR inhibitors has proven its worth for various types of tumours, possible side effects can be very stressful for patients. Scarring alopecia - permanent hair loss that can only be delayed but not reversed - is particularly cause for concern. Researchers at MedUni Vienna have now identified JAK inhibitors as active substances that can reactivate hair growth.

Helping out your neighbor or minding your own business? A challenging choice with different benefits for each decision. Game theory provides guidance in making such choices - from a theoretical perspective. Novel findings by Jakub Svoboda and Krishnendu Chatterjee at the Institute of Science and Technology Austria (ISTA) reveal new network structures that enhance cooperation throughout a system.

Non-native animals are a threat to biodiversity, yet many are themselves threatened with extinction in their areas of origin Non-native species introduced by humans are among the main causes of global species decline - they were partly responsible for 60 percent of the species that have become extinct worldwide in recent decades.

Advanced liver disease is the second most common cause of lost working years, as it disproportionately affects young patients. Possible complications of these diseases can often be traced back to high blood pressure in the blood circulation of the liver - portal hypertension. Under the leadership of Mattias Mandorfer from the Clinical Division of Gastroenterology and Hepatology at MedUni Vienna and University Hospital Vienna, the NICER model has now been developed, which can calculate the percentage probability of the presence of portal hypertension without an invasive procedure.

CLOUD project at CERN investigates particle formation of isoprene in the troposphere Aerosol particles in the atmosphere play a central role in cloud formation and consequently influence solar radiation on its way to Earth. An international team of scientists from the Universities of Vienna and Innsbruck is researching their formation and growth mechanisms.

When women are pregnant and nurse their babies, their bodies change and various organs, such as the breasts or the immune system, are adapted to ensure the health of both mother and child. This happens throughout evolution in all mammals. An international research team led by Josef Penninger and Masahiro Onji, Medical University of Vienna, now reports the surprising finding that the intestine also changes completely in pregnant and nursing females, resulting in a doubling of the intestinal surface area and a striking structural reorganisation.

Genetic study also reveals long-distance travelling in Neolithic societies An international team of researchers led by Pere Gelabert and Ron Pinhasi of the University of Vienna and David Reich of Harvard University has produced the most complete set of Early Neolithic genetic data from Central Europe to date.

A screening study carried out at MedUni Vienna has shown that the rare but dangerous infection with the hepatitis D virus remained often undetected. Seamless testing at University Hospital Vienna for the presence of a hepatitis D infection increases the diagnosis rate of this now treatable disease. The results of It is estimated that more than 40,000 people in Austria are chronically infected with the hepatitis B virus.

A research team at the Institute of Materials Chemistry at TU Wien, led by Professor Dominik Eder, has developed a new synthetic approach to create durable, conductive and catalytically active hybrid framework materials for (photo)electrocatalytic water splitting. Porous metal-organic framework catalysts The development of technologies for sustainable energy carriers, such as hydrogen, is essential.

New ISTA research shows how tissue development is temporally organized When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals are interpreted by developing cells remains unclear.

A team led by Francesca Ferlaino has set a new milestone in atomic physics by trapping individual erbium atoms in optical tweezers for the first time. Taking advantage of erbium's complex electronic structure, which opens up new degrees of freedom and possibilities, this advancement opens the door to a range of innovative experiments in quantum science.

ISTA scientists use harmless viruses to investigate the nervous system in frogs Amphibians hold a significant place in evolution, representing the transition from aquatic to terrestrial lifestyles. They are crucial for understanding the brain and spinal cord of tetrapods-animals with four limbs, including humans.

Secondary lymphoid organs are specialised structures in the body in which immune cells multiply and develop to respond to new pathogens such as viruses and bacteria. An international team led by Kaan Boztug (St. Anna Children's Cancer Research, MedUni Vienna, CeMM) has now been able to identify a completely new form of a rare disease that provides a better understanding of the importance of these structures for the human immune system.