Frontal part of a nematode seen through a microscope. The neurons of the worm’s "brain" are coloured in green. Above are the discs of light generated by the WF-TeFo microscope, scanning the brain area and recording the activity of certain neurons (artist’s interpretation) (Copyright: IMP)
Researchers in Vienna develop new imaging technique to study the function of entire nervous systems Scientists at the Campus Vienna Biocenter (Austria) have found a way to overcome some of the limitations of light microscopy. Applying the new technique, they can record the activity of a worm's brain with high temporal and spatial resolution, ultimately linking brain anatomy to brain function. publishes the details in its current issue. A major aim of today's neuroscience is to understand how an organism's nervous system processes sensory input and generates behavior. To achieve this goal, scientists must obtain detailed maps of how the nerve cells are wired up in the brain, as well as information on how these networks interact in real time. The organism many neuroscientists turn to in order to study brain function is a tiny, transparent worm found in rotting soil. The simple nematode C. elegans is equipped with just 302 neurons that are connected by roughly 8000 synapses.
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