Ronald Micura and Andrea Haller from the Institute for Organic Chemistry and the Center for Molecular Biosciences (CMBI) of the University of Innsbruck.
Chemists from Innsbruck and New York managed to monitor single-molecule switching in action. In an article in "Nature Chemical Biology" they report their findings: The secret of bacterial riboswitches lies in their dynamics. These findings are also relevant in antibiotics research. Photo: Ronald Micura and Andrea Haller from the Institute for Organic Chemistry and the Center for Molecular Biosciences (CMBI) of the University of Innsbruck. In various ways, bacteria are one step ahead to us humans. For example, they dispose of "intelligent" RNA molecules, so-called riboswitches, which help to regulate many of their essential metabolism pathways. The riboswitches, only discovered a few years ago, are sensors in RNA molecules.
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