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Autophagy: What to do with the waste in our cells? A 'waste collection' tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer's or Parkinson's may develop. Molecular biologist Sascha Martens from the University of Vienna together with international partners - researchers of the University of Pennsylvania, Monash University, the Max Planck Institute of Biophysics in Frankfurt and the UC Berkeley - investigate the associated process: autophagy.

Diversity of species arises through chromosomal mixing By comparing chromosomes of different animal groups scientists at the University of Vienna led by Oleg Simakov and at the University of California made an astonishing discovery: Every animal species has almost the same chromosomal units that appear over and over again - and this has been the case since the first animals emerged about 600 million years ago.

By Kerstin Lenk Astrocytes are non-neuronal brain cells that contribute to the exchange of neurotransmitters and ions. They are involved in various cognitive functions like sleep and memory formation. Using computational models, we simulate the interaction between neurons and astrocytes. By perturbing parts of the signaling pathways, we investigate astrocyte behavior in diseases like Alzheimer's, epilepsy, and schizophrenia.

German and Austrian scientists took a closer look at the braincase of a dinosaur from Austria. The group examined the fossil with a micro-CT and found surprising new details: it was sluggish and deaf. The respective study got recently published in the scientific journal scientific reports. Ankylosaurs could grow up to eight meters in body length and represent a group of herbivorous dinosaurs, also called 'living fortresses': Their body was cluttered with bony plates and spikes.

By analyzing ancient DNA an international team of scientists with participation of Ron Pinhasi's team of the University of Vienna was able to retrace the world's oldest family tree. They took samples from a Neolithic tomb in Britain. In their study published they reveal undiscovered information about the structure of prehistoric families.

By Christoph Pelzl Study led by TU Graz shows that apple trees inherit their microbiome to the same extent as their genes. The results lay the foundation for new breeding strategies for healthy and climate-robust fruit and vegetables. Agriculture is facing enormous challenges worldwide due to global changes caused by human activities.

Evolution led to similarities in the melodies of animal vocalizations and human languages When listening closely, the melodies of human languages and animal vocalizations are very similar. However, it is not yet fully resolved if similar patterns in languages and animal vocalizations also have similar meanings.

Distinct ecological niches: Tropical species profoundly alter ecosystem functioning in the Eastern Mediterranean Sea - with unknown consequences. Assemblages of tropical non-indigenous species in the Eastern Mediterranean have biological traits that markedly differ from those of native biological communities.

Extraordinary shape makes births more difficult, but guarantees stability The relatively narrow human birth canal presumably evolved as a "compromise" between its abilities for parturition, support of the inner organs, and upright walking. But not only the size of the birth canal, also its complex, "twisted" shape is an evolutionary puzzle.

Bacteria rapidly modify mobile parts of their genome to develop resistance to viruses Bacterial viruses, so-called phages, destroy bacteria. Bacteria are constantly exposed to viral attacks. A research team led by Martin Polz, a microbiologist at the University of Vienna, has now studied how bacteria defend themselves against viral predators.

By Beate Mosing The grey clouds of exhaust from industry are not only not a pretty sight, they are partially responsible for climate change, the effects of which we are now clearly experiencing. But it could also work differently. Turning waste streams, or more precisely, CO2, into a raw material is Regina Kratzer's declared goal.

By Christoph Pelzl For the first time ever, the intention of a continuous movement was able to be read out from non-invasive brain signals at TU Graz. This success enables more natural and non-invasive control of neuroprostheses to be carried out in real time. Intended to give paraplegic people back some freedom of movement and thus a better quality of life, so-called brain-computer interfaces (BCIs) measure the person's brain activity and convert the electrical currents into control signals for neuroprostheses.

By Birgit Baustädter Graz was instrumental in the birth of biomedical engineering in Austria 50 years ago - a step that laid the foundations for a long record of research successes. Today, numerous institutes work at the intersection between medicine and technology. "Optional subgroup IV Healthcare information".

Researchers discover biomarkers that indicate early brain injury in extreme premature infants Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.

Agriculture is the main source for the majority of the input of reactive N to terrestrial systems; large amounts of fertilizer N are lost from the root zone as nitrate through leaching and denitrification. Avoiding the combination of high external inputs with low resource use efficiency remains a major concern for the sustainability of N in agroecosystems.

This pandemic year has seen us confined to our homes and restricted from travelling the world. Not so for some microscopic bacteria in the ocean: Throughout the globe, they partner up with clams from the family Lucinidae, which live unseen in the sand beneath the shimmering blue waters of coastal habitats.

Ancient sediments from caves have already proven to preserve DNA for thousands of years. The amount of recovered sequences from environmental sediments, however, is generally low, which difficults the analyses to be performed with these sequences. A study led by Ron Pinhasi and Pere Gelabert of the University of Vienna and published in Current Biology successfully retrieved three mammalian environmental genomes from a single soil sample of 25,000 years bp obtained from the cave of Satsurblia in the Caucasus (Georgia).

Soil bacteria have amazing strategies to attain energy in order to withstand stressful times Soils are one of the most diverse habitats on the planet. There are more than thousand microbial species per gram that significantly influence numerous environmental processes. However, the majority of these organisms are believed to be in a state of 'dormancy' due to environmental stress, such as nutrient-poor conditions.

By Susanne Eigner The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research. Computer models have been standard tools in basic biomedical research for many years.

Similarity in axis formation of sea anemones and sea urchins provides insight into axis formation in prehistoric animals Body axes are molecular coordinate systems along which regulatory genes are activated. These genes then activate the development of anatomical structures in correct locations in the embryo.