Results 41 - 60 of 105.

Health - Pharmacology - 14.08.2023
Research into use of diabetes medication for treatment of metastatic prostate cancer
Patients with localised prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumour has not been fully explained. But an international research team headed by MedUni Vienna has succeeded in decoding the underlying cellular signal pathway and has carried out research using a common diabetes medication that could provide a new treatment option.

Health - Pharmacology - 09.08.2023
Childhood cancer: ’New’ immune system responds better to therapy
Scientists at Medical University Vienna/St. Anna Children's Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children. Crucially, stem cells from a parent provide children with a new immune system that responds much better to immunotherapies.

Pharmacology - 01.08.2023
New Study Sheds Light on the gating mechanism of Ion Channels
New Study Sheds Light on the gating mechanism of Ion Channels
Breakthrough achieved in elucidating the "gating" process of Kir2 potassium channels Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, either closed or open.

Health - Pharmacology - 31.07.2023
New method selectively inhibits lactate transporters and creates new therapeutic approaches
New method selectively inhibits lactate transporters and creates new therapeutic approaches
A research group led by Giulio Superti-Furga of the Institute of Pharmacology at the Medical University and the CeMM Research Center has developed a new method that makes it possible to specifically inhibit important lactate transporters associated with cancer and numerous other diseases. This could provide a new starting point for the treatment of cancer in particular.

Health - Pharmacology - 28.07.2023
New method enabling therapeutical targeting of lactate transporters
New method enabling therapeutical targeting of lactate transporters
Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate transporter associated with cancer and other disease areas. The compound identified in the assay system could provide a new starting point for cancer treatments.

Health - Pharmacology - 05.07.2023
Peritoneal dialysis: New treatment option against infections
Peritoneal dialysis: New treatment option against infections
Inflammations of the peritoneum (peritonitis) are as frequent as they are feared complications in peritoneal dialysis, a form of kidney replacement therapy for independent use at home. The bacteria responsible for the life-threatening infections are becoming increasingly resistant to many antibiotics.

Health - Pharmacology - 20.06.2023
Prediction tool developed to determine benefit of blood cancer treatment
Prediction tool developed to determine benefit of blood cancer treatment
Since its introduction in 2015, a prediction tool developed by the European Society of Medical Oncology (ESMO) has been providing support worldwide in the assessment of the clinical benefits of new cancer therapies. However, previously available versions proved unsuitable for use with malignant diseases of the blood, such as different types of leukaemias or lymphomas.

Health - Pharmacology - 23.05.2023
Covid-19 vaccination reduces mortality also in critically ill corona patients
Covid-19 vaccination reduces mortality also in critically ill corona patients
A study from the University of Vienna shows a positive effect of vaccination even in patients requiring oxygen. Previous studies have shown that the mortality rate of Corona patients hospitalized and requiring oxygen therapy is similar no matter if they are vaccinated or unvaccinated.

Pharmacology - Health - 17.05.2023
New treatment method for chronic lymphocytic leukemia
A recent study involving MedUni Vienna and University Hospital Vienna has identified a significant advance in the treatment of chronic lymphocytic leukaemia (CLL). The results of the randomised Phase III CLL13 (GAIA) study show that a time-limited and targeted therapy with venetoclax and obinutuzumab is more effective than chemoimmunotherapy in patients without comorbidities.

Health - Pharmacology - 10.05.2023
Common Variable Immunodeficiency: Role of B-cell selection identified
Common Variable Immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency in humans. Patients suffer from recurrent infections of the upper and lower respiratory tract but many of them also develop more severe symptoms such as granulomas, lymphomas and autoimmune diseases. An international team of researchers led by MedUni Vienna has now discovered why some CVID patients develop an autoimmune disease and others do not.

Pharmacology - Health - 04.05.2023
Paradigm shift in the treatment of metastatic colorectal cancer
A global study led by Gerald Prager of the Department of Medicine I and the Comprehensive Cancer Center (CCC) Vienna, a joint MedUni Vienna and University Hospital Vienna facility, and co-workers has demonstrated that the prognosis for patients with metastatic colorectal cancer can be significantly improved.

Health - Pharmacology - 04.05.2023
Faecal incontinence: New surgical treatment being tested at University Hospital Vienna and MedUni Vienna
Faecal incontinence is a major taboo subject and, if left untreated, usually restricts the quality of life of those severely affected. Under the leadership of surgeon Stefan Riss from the Department of General Surgery at MedUni Vienna and the University Hospital Vienna, a study has been launched into a new surgical treatment method.

Health - Pharmacology - 27.04.2023
Chronic thromboembolic pulmonary vascular disease and left heart disease are not mutually exclusive
A long-term analysis designed by Christian Gerges and Irene Lang at the Department of Medicine II of the University Hospital Vienna and MedUni Vienna indicates that one third of patients with chronic thromboembolic pulmonary hypertension (CTEPH) also have left heart disease. In the past, the possibility of overlap between these two conditions had not been considered in the diagnosis and treatment of CTEPH patients.

Health - Pharmacology - 05.04.2023
Morbus Crohn: New imaging technique for effective therapy
Patients suffering from Crohn's disease, a chronic inflammatory intestinal disorder, develop painful constrictions in the bowel. Due to a lack of methods until now, these complications cannot be characterised with sufficient precision to initiate targeted treatment. An interdisciplinary research group at MedUni Vienna has investigated a new imaging technique that can improve the treatment of intestinal strictures.

Health - Pharmacology - 04.04.2023
Transplantation medicine: Novel insights into immunosuppressive mechanism of ATG identified
Medicine & Science A team of researchers at MedUni Vienna has newly appraised the immunosuppressive effect of antithymocyte globulin (ATG) and identified a previously unknown mode of action. The new findings on ATG, which are used for induction therapy prior to organ transplantations and for the treatment of T-cell mediated rejection reactions, provide a new approach for further improvements in transplantation medicine.

Pharmacology - Health - 27.03.2023
Hereditary angioedema: New drug being researched
Medicine & Science In the case of the rare genetic disease of hereditary angioedema (HAE), swelling occurs in one or more parts of the body without a recognisable trigger. An HAE attack can be life-threatening especially if the upper respiratory tract is affected. Active substances for on-demand medication are currently only available in the form of injections and transfusions.

Health - Pharmacology - 27.03.2023
Covid-19 vaccination fatigue on the rise: researchers analyse measures aimed at increasing booster uptake
Medicine & Science With vaccination fatigue growing and the emergence of new coronavirus variants a possibility, health officials face a potential challenge when it comes to encouraging the public to get regular boosters to protect them against Covid-19.

Health - Pharmacology - 20.03.2023
Traditional Chinese Medicine: Great trust, little evidence
Studies & Further Education People in Austria have great confidence in Traditional Chinese Medicine (TCM). According to the World Health Organisation (WHO), diagnostic and therapeutic methods of TCM should also be strengthened further in national healthcare systems. A recent publication by MedUni Vienna found a clear divergence between the perceived and actual scientific character of TCM.

Health - Pharmacology - 20.03.2023
SARS-CoV-2: Only neutralising antibodies allow conclusions to be drawn about protection against new infections
Medicine & Science Mutations of virus and illnesses caused by new variants are still to be expected even in a SARS-CoV-2 situation that has now become endemic. Although the population has developed specific immune responses due to previous infections and vaccinations, vaccinated and vulnerable individuals continue to contract COVID-19.

Health - Pharmacology - 17.03.2023
Small cell lung cancer: New therapy option being explored
Medicine & Science Small cell lung cancer (SCLC) accounts for 15% of all lung cancer cases and is still associated with a particularly high mortality rate. According to a recent multicenter study led by MedUni Vienna, SCLC can be classified into specific molecular subtypes. New research from the same international team now suggests that a novel combination drug therapy could be an effective option for patients with specific molecular backgrounds.