Results 21 - 40 of 354.

Health - Life Sciences - 10.04.2024
Key interaction of molecules discovered to influence hormone release
In a study recently published in the scientific journal PNAS, a research team led by MedUni Vienna has presented results that show a new way for drug development for post-traumatic stress disorder, alongside other indications. Although around four per cent of the population suffer from this mental illness, only symptomatic therapies are currently available.

Health - 08.04.2024
Cardiac surgery: New total endoscopic surgical method for complex re-operations of the tricuspid valve
Cardiac surgery: New total endoscopic surgical method for complex re-operations of the tricuspid valve
At the Department of Cardiac Surgery at University Hospital Vienna and MedUni Vienna, an innovative operation on the tricuspid valve, the inlet valve of the right ventricle, was performed for the first time in Austria, in which neither the sternum had to be opened nor the heart stopped.

Life Sciences - Health - 05.04.2024
The membrane that surrounds the embryo in the earliest stage of development
A MedUni Vienna study team led by geneticist Markus Hengstschläger has used a stem cell model to model the earliest stages of embryonic development and to characterize the membrane that surrounds the embryo, conferring shape and stability. This membrane is responsible for the specification and organization of the embryo's cells and allows it to grow in a controlled manner.

Environment - Health - 04.04.2024
How Plants Heal Wounds
How Plants Heal Wounds
April 4, 2024 Pressure changes and mechanical forces trigger wound healing in plants Plants are very robust and survive harsh environments, owing in part to their remarkably efficient wound-healing capacity. For over a century, scientists aimed to understand it in more detail. A new collaborative study at the Institute of Science and Technology Austria (ISTA) now shows that the process is quite straightforward, revolving around pressure and forces.

Health - History / Archeology - 29.03.2024
Crimean-Congo Fever: molecular mechanism of infection discovered
The Crimean-Congo Haemorrhagic Fever virus (CCHFV), first described in 1944, is also spreading rapidly in Europe due to global warming and is included in the WHO list of infectious agents with epidemic or pandemic potential as a top priority. There are currently no therapeutic or preventative measures available against the disease, which is mainly transmitted by ticks and is fatal in 40 per cent of cases.

Health - Life Sciences - 28.03.2024
Cell research: New lysosomal dipeptide transporter described
In a recently published research paper, led by Marko Roblek from MedUni Vienna's Center for Physiology and Pharmacology, the function of a specific protein (SLC MFSD1) as a dipeptide transporter has been described for the first time. Dysregulation of MFSD1 is associated with liver disease, lymphocyte formation disorders and tumor metastasis, making these proteins highly relevant clinically.

Health - Life Sciences - 27.03.2024
Energy requirements for T cell functionality decoded
A research team led by Loïc Dupré (Department of Dermatology, MedUni Vienna) has conducted experiments to identify a coordinated molecular axis that governs the functionality of T cells. The study reveals how the availability of cellular energy controls the remodelling of the actin cytoskeleton, a central cellular activity that determines the ability of T cells to migrate and establish dynamic contacts.

Health - Pharmacology - 25.03.2024
Progress made in understanding Crohn’s disease
Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments. By analysing draining mesenteric lymph nodes of affected small intestinal segments of patients who had required surgery, a research team led by Lukas Unger from MedUni Vienna identified immune responses that improve our understanding of the disease.

Health - Pharmacology - 22.03.2024
Cervical cancer: immunotherapy proven to improve prognosis
Cervical cancer: immunotherapy proven to improve prognosis
Since 1999, the standard treatment for locally advanced cervical cancer has consisted of external radiotherapy followed by chemotherapy and brachytherapy. As the prognosis for patients is still poor in many cases despite these measures, intensive research is being conducted into new options. In a large-scale clinical trial, an international team involving MedUni Vienna has shown that the immunotherapeutic agent pembrolizumab in combination with chemoradiotherapy leads to a statistically significant improvement compared to chemoradiotherapy alone.

Health - 21.03.2024
Cardiac amyloidosis: New AI system developed for early diagnosis
Cardiac amyloidosis is a serious disease in which abnormal proteins (amyloids) accumulate in the heart muscle and impair heart function. As the disease leads to serious complications such as heart insufficiency and, in many cases, death if left untreated, early diagnosis is essential in order to start treatment in good time.

Health - Pharmacology - 15.03.2024
New insights could improve treatment of liver fibrosis
Repeated or chronic liver injury, for example by viral hepatitis or alcohol consumption, triggers a complicated molecular process of scaring called liver fibrosis. Researchers at CeMM and MedUni Vienna have now succeeded in better understanding this process in a new study by examining gene activities at various stages of the liver disease.

Health - Pharmacology - 13.03.2024
New findings on the prevention of heart attacks and strokes
New findings on the prevention of heart attacks and strokes
Blockage of arterial blood vessels caused by atherosclerosis is largely responsible for heart attacks and strokes, which are the most common causes of death worldwide. The complex mechanisms that lead to pathological changes in the arteries are not yet fully understood. An international research team led by the Medical University of Vienna and the University Hospital of Würzburg has now made important progress in understanding this disease and identified potential new approaches for early detection and therapy.

Pharmacology - Health - 11.03.2024
Further developed COVID vaccine from MedUni Vienna shows promising results against Omikron
Researchers at the Center for Pathophysiology, Infectiology and Immunology at the Medical University of Vienna have further developed their Covid-19 vaccine, which has now shown promise in the fight against the Omikron variant of the virus. The results of their work were recently published in the top journal "Vaccines".

Health - Career - 08.03.2024
Female doctors give high marks for working conditions in primary care centers
Female doctors generally rate the working conditions in primary care units (PCUs) highly. This is the result of a recent survey conducted by MedUni Vienna on work-life balance and satisfaction among female doctors working in primary care units. According to the study, there is a need to catch up in the areas of distribution of working hours and time for additional activities such as external teaching or further training.

Health - 07.03.2024
New model for the early detection of diseases
In a recent study, researchers from the Complexity Science Hub and MedUni Vienna are analysing the entire health trajectory of almost nine million people in Austria for the first time. They identify critical points at which disease progression drifts apart significantly - with serious consequences for the lives of patients and for the healthcare system.

Health - Chemistry - 06.03.2024
Micro- and nanoplastics in the body are passed on during cell division
The gastrointestinal tract is already known to researchers as a major storage site for microand nanoplastic particles (MNPs) in the human body. A research consortium consisting of the University of Vienna, the Medical University of Vienna and other partners under the leadership of CBmed GmbH in Graz has now investigated the effects of the tiny plastic particles on cancer cells in the human gastrointestinal tract.

Life Sciences - Health - 29.02.2024
Significant progress in bionic reconstruction of limb functions
Significant progress in bionic reconstruction of limb functions
Bionic reconstruction, in which functionless limbs are replaced by mechatronic limbs, can restore mobility and quality of life to accident patients. However, the high-resolution transmission of information from the brain to the machine remains a demanding challenge. An interdisciplinary research team led by Vlad Tereshenko and Oskar Aszmann from MedUni Vienna's Department of Plastic, Reconstructive and Aesthetic Surgery has now made further significant progress as part of a study.

Health - Life Sciences - 27.02.2024
Immune system meets cancer: Checkpoint identified to fight solid tumors
Immune system meets cancer: Checkpoint identified to fight solid tumors
Checkpoint PHDGH in tumor-associated macrophages influences immune response and tumor growth A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology , has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

Health - 20.02.2024
Key cells in chronic sarcoidosis uncovered
The latest research findings from MedUni Vienna provide insights into the molecular mechanisms underlying chronic sarcoidosis, a complex granulomatous disease with limited treatment options. The scientific team, led by Thomas Weichhart and Georg Stary, presents new findings that challenge the conventional understanding of the disease and proposes a new therapeutic approach.

Health - Pharmacology - 15.02.2024
Chronic fatigue syndrome: number of patients is expected to double due to long-term effects of the COVID-19 pandemic
Up to 80,000 people in Austria are estimated to suffer from chronic fatigue syndrome, also known as ME/CFS or myalgic encephalomyelitis/chronic fatigue syndrome. The number of ME/CFS patients is expected to rise drastically due to long-term effects of the COVID-19 pandemic. However, research in the field has neither identified mechanisms of disease onset nor causal treatment approaches.