Results 61 - 80 of 105.

Pharmacology - Chemistry - 10.03.2023
Nano shag brushes bring active ingredients into body
Newly developed nanoparticles in the form of tiny shag brushes effectively transport drugs through the body . Once their work is done, they are degraded into natural precursors, releasing active substances that they have brought with them, explained Ian Teasdale of the Institute of Chemistry of Polymers at Johannes Kepler University Linz.

Health - Pharmacology - 03.03.2023
Erdem Yildiz receives Spoendlin Junior Award for outstanding research work
People of the MedUni Vienna Erdem Yildiz from the University Department of Otorhinolaryngology received the internationally renowned Spoendlin Junior Award for young basic scientists in hearing research for his research work "Investigation of Inner Ear Drug Delivery with a Cochlear Catheter in Piglets as a Representative Model for Human Cochlear Pharmacokinetics".

Life Sciences - Pharmacology - 23.02.2023
New CD Laboratory: Folding Proteins Correctly
New CD Laboratory: Folding Proteins Correctly
When proteins are produced in the pharmaceutical industry, they are often initially misfolded and have to be rearranged. At TU Wien, this is being studied in detail in a new CD laboratory . Certain proteins are among the most important products of the pharmaceutical industry - such as insulin or interferons, which are used to treat diabetes, cancer or viral diseases.

Pharmacology - Health - 03.02.2023
Adapting drugs to DNA results in a 30% reduction in side-effects
Medicine & Science An international research group, including scientists from MedUni Vienna and led by Leiden University Medical Center, has found that patients have 30% fewer serious side-effects when the drug dose is adapted to their DNA. The study, published in "The Lancet", is the first to demonstrate the practical application of prescribing drugs based on a person's genetic information.

Health - Pharmacology - 31.01.2023
New method for therapy selection in precision medicine explored
Medicine & Science A study led last year by Wolfgang Schreiner from MedUni Vienna demonstrated the advantage of decision theory as a valuable extension of conventional statistics in therapy selection in precision medicine. In a research study based thereon, a new method was investigated to render medical decisions more justifiable and independent of intuitions.

Health - Pharmacology - 30.01.2023
World Cancer Day 2023: With Tumour profiling for customised therapy
Medicine & Science The cancer therapy of the future is increasingly customised in the sense of precision medicine. The basis for this is comprehensive "profiling" of each individual tumour, which extensively analyses the genetic make-up of the individual tumour at molecular level. This "comprehensive cancer profiling" is already being used at the Comprehensive Cancer Center Vienna (CCC) of MedUni Vienna and Vienna General Hospital for all types of cancer and permits the identification of changes in a tumour that argue for or against the use of a particular therapy.

Health - Pharmacology - 24.01.2023
Alcohol-related liver disease: mechanism could form basis for development of new therapies
Medicine & Science Alcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of the factors contributing to disease development, liver transplantation is still the only available cure. A team led by Tim Hendrikx from MedUni Vienna's Department of Laboratory Medicine has now uncovered a new mechanism that plays an important role in the progression of the disease.

Health - Pharmacology - 23.01.2023
Covid-19 in pregnant women can damage the placenta and the foetus
Medicine & Science Using prenatal magnetic resonance imaging, a group of MedUni Vienna researchers examined the placentas and foetuses of women who tested positive for SARS-CoV-2 during pregnancy. Their research results demonstrate that the different strains of the virus that emerged during the pandemic led to varying degrees of damage: especially involving pre-Omicron variants, the detected placental lesions could potentially harm both development and health in some of the affected unborn children.

Health - Pharmacology - 09.01.2023
New biomarker for early prediction of response to CAR-T cell therapy
A MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequisites for optimal use of this novel therapy for lymphoma treatment. The current findings are an essential step forward towards optimizing this promising therapy.

Health - Pharmacology - 05.01.2023
Locally advanced cervical cancer: Better odds using personalized brachytherapy
Cervical cancer is the cancer with the fourth highest mortality rate among women worldwide. Locally advanced cervical cancer (LACC) is treated with a combination of external and internal radiotherapy (brachytherapy) and chemotherapy. For the first time, a study conducted by a research group at the Comprehensive Cancer Centre Vienna of MedUni Vienna and Vienna General Hospital using data from the multicentre EMBRACE-I trial demonstrated the superiority of a targeted approach in brachytherapy.

Health - Pharmacology - 29.12.2022
Immune signature discovered for Long Covid
Severe covid 19 disease is characterized by excessive immune and inflammatory processes in the body. Conversely, long covid syndrome is likely to have a strong anti-inflammatory immune status. Scientists have now found this out with extensive blood plasma analyses of vaccinated persons without subsequent disease, persons with completely survived covid 19 infection and long covid patients.

Health - Pharmacology - 19.12.2022
Relationship between high-dose statin therapy and risk of osteoporosis confirmed in mouse models
Using several million medical records, a research group from MedUni Vienna and the Complexity Science Hub (CSH) showed that there was a correlation between the dosage of statins and the diagnosis of osteoporosis as early as 2019. This finding has now been confirmed in a preclinical study, which was recently published in the journal Biomedicine and Pharmacotherapy.

Health - Pharmacology - 15.12.2022
Long COVID: New evidence for cause of fatigue syndrome
The diagnosis and treatment of long COVID syndrome (LCS) is still very difficult, and there is only little knowledge about the factors causing accompanying symptoms. Researchers at the Joint Metabolome Facility of the University of Vienna and the Medical University of Vienna have now presented new evidence of triggers for fatigue following SARS-COV-2 infection.

Health - Pharmacology - 13.12.2022
Alcohol abstinence essential even in advanced liver cirrhosis
Complete abstinence from alcohol is considered a cornerstone in the treatment of patients with alcohol-related liver disease. It has not yet been sufficiently researched whether this measure can still improve the prognosis even in the case of advanced liver cirrhosis. Scientists at the Department of Internal Medicine III at MedUni Vienna and AKH Vienna have now provided evidence of the positive effects of alcohol abstinence even at very advanced stages of the disease.

Pharmacology - Health - 12.12.2022
Light therapy relieves fatigue syndrome in Multiple Sclerosis
Light therapy relieves fatigue syndrome in Multiple Sclerosis
Multiple Sclerosis (MS) is almost always accompanied by fatigue, a massive tiredness that is described by the vast majority of patients as the most distressing symptom. In a recent scientific study, a research group led by Stefan Seidel from the Department of Neurology at MedUni Vienna and AKH Vienna identified light therapy as a promising non-drug treatment option: patients included in the study showed a measurable improvement after just 14 days of use.

Health - Pharmacology - 06.12.2022
Emergency medicine: Correlation between electrolyte administration in atrial fibrillation and return to regular heartbeat
Patients receiving emergency medical treatment for atrial fibrillation show a correlation between the intravenous administration of potassium and magnesium and a spontaneous return to a normal heart rhythm. This was discovered in a new study by the Department of Emergency Medicine at MedUni Vienna and University Hospital Vienna, which analysed patient data between 2009 and 2020.

Health - Pharmacology - 17.11.2022
Obesity: research focuses on treatments for secondary diseases
As the number of obese people suffering from related conditions such as liver disease increases, so does the need for research to develop interventions to improve patient care. The Christian Doppler Laboratory, which opened today at MedUni Vienna, is investigating the physiological basis of the consequences of obesity.

Pharmacology - Health - 15.11.2022
Potential new lead compounds for the treatment of depression and anxiety disorders
Potential new lead compounds for the treatment of depression and anxiety disorders
Currently, various classes of drugs are available for the treatment of mental illnesses - such as depression and anxiety disorders. However, although these drugs confer benefits, they are also associated with adverse side-effects. Conseqeuntly, medical researchers continuously thrive to improve the pharmacological properties of therapeutic agents to optimize the benefit-to-side-effect ratio.

Health - Pharmacology - 25.08.2022
New drug expands treatment opportunities for rheumatoid arthritis
In its final Phase III clinical trial, a new drug for treating rheumatoid arthritis has proved to be at least as effective as the current "gold standard" treatment for this autoimmune disease. This opens up new treatment options for affected patients. The results of the international multicentre study led by MedUni Vienna were recently published in the prestigious "New England Journal of Medicine".

Pharmacology - Health - 22.06.2022
Mugwort allergy: MedUni Vienna study creates basis for vaccine
A research team at MedUni Vienna has discovered key mechanisms of allergy to pollen from the common weed mugwort, thereby also laying the foundation for the development of the world's first vaccine. Mugwort (Artemisia vulgaris) poses a serious problem for allergic individuals in our latitudes from July through to September.