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Life Sciences - Health - 09.04.2021
Popeye with a whiff of rotten eggs
Popeye with a whiff of rotten eggs
A sulfosugar from green vegetables promotes the growth of important gut bacteria An international team of scientists led by microbiologists Alexander Loy from the University of Vienna and David Schleheck from the University of Konstanz has uncovered new metabolic capabilities of gut bacteria. For the first time, the researchers have analyzed how microbes in the gut process the plant-based, sulfur-containing sugar sulfoquinovose.

Health - Psychology - 15.03.2021
Fear of COVID-19 : Psychological, not environmental factors are important
Fear of COVID-19 : Psychological, not environmental factors are important
During pandemics, protective behaviors need to be motivated by effective communication. A critical factor in understanding a population's response to such a threat is the fear it elicits, since fear both contributes to motivating protective responses, but can also lead to panic-driven behaviors. Furthermore, lockdown measures affect well-being, making it important to identify protective factors that help to maintain high perceived levels of health during restrictions.

Health - Life Sciences - 05.03.2021
Promising metallodrug candidate for tumour therapy
Promising metallodrug candidate for tumour therapy
BOLD-100/KP1339 is a ruthenium-based anticancer agent that has been decisively co-developed at the University of Vienna and which has shown promising results in clinical trials in cancer patients. However, the mode of action of this metal compound has not yet been fully elucidated. Researchers from the University of Vienna and the Medical University of Vienna have now been able to demonstrate that BOLD-100 binds to ribosomal proteins in tumour cells.

Pharmacology - Health - 09.02.2021
The therapeutic potential of peptides
The therapeutic potential of peptides
Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases such as diabetes, cancer, hormone disorders, HIV infection, and multiple sclerosis.

Health - Computer Science - 22.01.2021
Cardiovascular diseases: New computer model improves therapy
Cardiovascular diseases: New computer model improves therapy
Using mathematical image processing, scientists at the BioTechMed-Graz research cooperation have found a way to create digital twins from human hearts. The method opens up completely new possibilities in clinical diagnostics. Additional Images for download at the end of the text Although treatment options are constantly improving, cardiovascular diseases are still one of the most frequent causes of death in Europe.

Life Sciences - Health - 11.01.2021
Resistant rice plants: TU Graz identifies bacterium that protects rice plants against diseases
Resistant rice plants: TU Graz identifies bacterium that protects rice plants against diseases
With their expertise in microbiome research, the researchers at the Institute of Environmental Biotechnology were able to demonstrate how a specific bacterium inside the seeds of rice plants effectively and in an eco-friendly way inhibits destructive plant pathogens. Rice is the staple food of about half the world's population.

Health - Innovation - 22.12.2020
Adaptive, automated, interactive: Graz research group develops health portal of the future
Adaptive, automated, interactive: Graz research group develops health portal of the future
Researchers from TU Graz, Med Uni Graz and Uni Graz are working on a digital interactive information system that automatically tailors medical content to individuals and their needs. Additional Images for download at the end of the text Can this digital medium make predictions about the individual information needs of users, recognize their cognitive abilities, and use this data to convey high-quality medical content in a comprehensible and clear manner?

Pharmacology - Health - 01.12.2020
Environmental exposures affect therapeutic drugs
Environmental exposures affect therapeutic drugs
High-resolution mass spectrometry promotes new methods for analysis Humans are exposed to various environmental or dietary molecules that can attenuate or even increase the effect of therapeutic drugs. Studies on the industrial chemical bisphenol A and the phytoestrogen genistein, for example, have shown drug-exposome interactions.

Health - Life Sciences - 05.11.2020
Graz researchers identify biomarker for cardiovascular diseases
Graz researchers identify biomarker for cardiovascular diseases
The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases. The renin-angiotensin system (RAS) becomes active at low blood pressure and forms angiotensin II, a hormone that causes blood vessels to constrict, causing blood pressure to rise again.

Health - Life Sciences - 27.10.2020
New cancer diagnostics: A glimpse into the tumor in 3D
New cancer diagnostics: A glimpse into the tumor in 3D
In order to analyze tumors, they have to be cut into thin slices. Now, a new technology has been developed that makes pieces of the tumor visible in 3D without cutting them. After cancer surgery, the crucial question is: Are there possibly cancer cells left behind that can continue to grow, or has the entire tumor actually been removed? To find out, the tumor is examined by pathologists.

Health - Mechanical Engineering - 19.10.2020
COVID-19: Distancing and Masks are not Enough
COVID-19: Distancing and Masks are not Enough
Decades-old data is being used to describe the propagation of tiny droplets. Now a fluid dynamics team has developed new models: Masks and distancing are good, but not enough. 1/2 images Droplets with a viral load [Translate to English:] Tröpfchen haben begrenzte Reichweite, Aeorsole können aber größere Distanzen überbrücken [Translate to English:] Tröpfchen haben begrenzte Reichweite, Aeorsole können aber größere Distanzen überbrücken Wear a mask, keep your distance, avoid crowds - these are the common recommendations to contain the COVID-19 epidemic.

Health - Life Sciences - 02.09.2020
COVID-19: Virale RNA auch mehrere Tage nach dem Tod noch vorhanden
Ein ForscherInnen-Team um Sigurd Lax, Professor für Pathologie an der Johannes Kepler Universität Linz und Vorstand des Instituts für Pathologie des Landeskrankenhauses Graz II hat gemeinsam mit Kollegen der Medizinischen Universität Graz und der Medizinischen Universität Wien eine Studie zur postmortalen Virendynamik von SARS-CoV-2 veröffentlicht.

Life Sciences - Health - 10.06.2020
Cellular stress causes cancer cell chemoresistance
Cellular stress causes cancer cell chemoresistance
Postgenomic technologies reveal new mechanism of stress-induced chemoresistance Resistance of cancer cells against therapeutic agents is a major cause of treatment failure, especially in recurrent diseases. An international team around the biochemists Robert Ahrends from the University of Vienna and Jan Medenbach from the University of Regensburg identified a novel mechanism of chemoresistance which has now been published in "Nature Communications".

Health - Pharmacology - 21.04.2020
Milestone for the early detection of sepsis
Milestone for the early detection of sepsis
Researchers from Graz, Austria, are developing a ground-breaking method that uses biomarkers to detect sepsis 2 to 3 days before the first clinical symptoms appear. This can significantly increase the chances of survival in cases of blood poisoning by bacteria or fungi. Additional pictures for download at the end of the text Whether activating or silencing genes, breaking down defective cells or building new tissue, our body is constantly working to repair itself, even in cases of illness.

Health - Life Sciences - 05.02.2020
Targeting the cancer microenvironment
Targeting the cancer microenvironment
Researchers discover a novel checkpoint in immune cells with the potential to treat the cancer cell microenvironment The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.

Life Sciences - Health - 11.10.2019
New method for quicker and simpler production of lipidated proteins
New method for quicker and simpler production of lipidated proteins
The new method developed at TU Graz and the University of Vienna is leading to a better understanding of natural protein modifications and improved protein therapeutics. Additional pictures for download at the end of the text Some of the body's proteins are not just made up of amino acids, they are also 'decorated' with lipid chains, which significantly influence the biological functions of the protein.

Health - 04.07.2019
The ancestor of the great white shark
The ancestor of the great white shark
The unique tooth structure of the great white shark gives new insights into its origin Mackerel sharks (Lamniformes) are a group consisting of some of the most iconic sharks we know, including the mako shark (the fastest shark in the world), the infamous great white shark and Megalodon, the biggest predatory shark that has ever roamed the world's oceans.

Health - Life Sciences - 18.06.2019
Antidepressants can reduce the empathic empathy
Antidepressants can reduce the empathic empathy
Antidepressant treatment, not only depression per se, can lead to reductions in behavioral and neural responses to pain empathy Depression is a disorder that often comes along with strong impairments of social functioning. Until recently, researchers assumed that acute episodes of depression also impair empathy, an essential skill for successful social interactions and understanding others.

Health - Life Sciences - 14.05.2019
Symbionts as lifesavers
Symbionts as lifesavers
Researchers discover new factor influencing the spread of Legionella When people fall ill from bacterial infection, the first priority is to treat the disease. But where do these pathogens come from and how do they thrive in the environment before the infection occurs' An international team led by Matthias Horn from the Centre for Microbiology and Environmental Systems Science at the University of Vienna has tackled this question using an important bacterial pathogen that causes lung disease.

Life Sciences - Health - 07.03.2019
Excessive hygiene promotes resistance to antibiotics
Excessive hygiene promotes resistance to antibiotics
, researchers from Graz, Austria present new perspectives to prevent the spread of antibiotic resistances in hospitals. Additional pictures for download at the end of the text. The number of people who die from antibiotic-resistant germs is increasing worldwide. The World Health Organization WHO considers the spread of antibiotic resistance and appropriate countermeasures as one of the most important global challenges nowadays.
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