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Results 1 - 20 of 26.


Health - Pharmacology - 16.07.2024
New approach to improve targeted skin cancer therapies
Targeted therapies are a powerful weapon against skin cancer, but their side effects can severely impact a patient's quality of life. A new study shows that some targeted therapies manipulate signaling events in cells that line blood vessels and result in a weaker vascular barrier. This knowledge sheds some light on possible mechanisms leading to side effects and it can contribute to the development of better therapies for skin cancer.

Health - Pharmacology - 15.07.2024
SARS-CoV-2 infections have a long-term impact on the immune systemg
In a study recently published in the renowned journal "Allergy", a MedUni Vienna research team shows that COVID-19 leads to considerable long-term changes in the immune system, even in mild cases. The findings could help to better understand the long-term consequences of an infection with SARS-CoV-2.

Health - Pharmacology - 09.07.2024
Active substance identified for the prevention of chlamydial infections
Despite the significant increase in sexually transmitted diseases in recent years, there is currently no vaccine available against common bacterial pathogens such as chlamydia. In the search for ways to prevent infection, a research team from MedUni Vienna and the CeMM Research Center for Molecular Medicine has identified the active substance pentamidine as a promising candidate for the prophylaxis of chlamydial infections and possibly other bacterial sexually transmitted diseases.

Health - Pharmacology - 27.06.2024
Non-invasive tests for liver health
Non-invasive tests for liver health
Advanced liver disease is the second most common cause of lost working years, as it disproportionately affects young patients. A scientific team from MedUni Vienna has been able to determine a threshold value for a simple blood test that can be used to identify people with an increased risk of complications, even without special testing.

Pharmacology - Psychology - 25.06.2024
Psychoactive agents in psychotherapy: New MDMA variants identified for potentially safer use
The use of the active ingredient 3,4-methylenedioxy-N-methylamphetamine (MDMA), commonly known as "ecstasy", to support psychotherapy for mental illnesses such as post-traumatic stress disorder is being discussed worldwide. While the therapeutic potential of the substance has already been investigated in clinical trials, only Australia and New Zealand have so far decided to approve and restrict its controlled use by experts due to possible risks and side effects.

Health - Pharmacology - 04.06.2024
Heart: New heart valve prosthesis enables broader applicability
A catheter-based tricuspid valve replacement with a newly approved heart valve was performed for the first time in Austria at University Hospital Vienna and MedUni Vienna. The new heart valve prosthesis now also makes it possible to treat patients who could previously only be treated with medication for anatomical reasons or due to the cause of the heart valve leak.

Health - Pharmacology - 03.06.2024
New findings on the prevention of rejection reactions in organ transplants
Immunosuppressive drugs protect transplanted organs from harmful immune reactions. Nevertheless, rejection reactions can still occur. A MedUni Vienna research team led by Thomas Wekerle has deciphered mechanisms that lead to rejection despite the use of the latest immunosuppressive drugs. These findings point to new therapeutic options for preventing such rejection reactions in the future.

Pharmacology - Health - 27.05.2024
New therapy proven effective against rejection in kidney transplantation
New therapy proven effective against rejection in kidney transplantation
Antibody-mediated rejection (AMR) is one of the most common causes of kidney transplant failure. To date, however, no treatment has proven effective in combating this complication in the long term. As part of an international and multidisciplinary clinical study led by Georg Böhmig and Katharina Mayer, Clinical Division of Nephrology and Dialysis, Department of Medicine III at MedUni Vienna and University Hospital Vienna, a new therapeutic principle in transplant medicine has been found to be both safe and highly effective.

Health - Pharmacology - 13.05.2024
Limited efficacy of common local anaesthetic
Liposomal bupivacaine was launched on the market twelve years ago to provide long-lasting local control of pain. The medication is used as a local anaesthetic, particularly for orthopaedic operations. A research study by MedUni Vienna has now shown the limited effectiveness of the substance. The study has just been published in the journal "Anesthesiology", the peer-reviewed journal of the American Society of Anesthesiologists (ASA).

Health - Pharmacology - 02.05.2024
Immunotherapy for lung cancer effective even before surgery
Blocking "switches" of the immune system has revolutionized the treatment of patients with various metastatic cancers. In 2018, the discovery of this principle was recognized by the Nobel Prize in Medicine. An international research team has now shown that the simultaneous inhibition of two "immune switches", PD-1 and LAG-3, can lead to the killing of lung cancer cells after just a few weeks.

Pharmacology - Health - 29.04.2024
New phytocannabinoid discovered in sweet violet
New phytocannabinoid discovered in sweet violet
Cannabinoids are endogenous hormones or naturally occurring molecules found in various plants, most commonly known as THC (?9-tetrahydrocannabinol) in cannabis plants. The therapeutic potential of these compounds is the subject of intensive research, yet their psychoactive and addictive properties stimulate intensive debate.

Health - Pharmacology - 23.04.2024
Liver cancer: Molecular signalling pathway of tumour development decoded
Liver cancer: Molecular signalling pathway of tumour development decoded
As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths. While the treatment options for this aggressive type of cancer remain limited, the incidence is increasing. A research team led by Latifa Bakiri and Erwin Wagner from MedUni Vienna's Clinical Institute for Laboratory Medicine has now described a molecular signalling pathway that plays a key role in the development of liver cancer, thereby identifying a potential new starting point for the development of therapeutic treatments.

Health - Pharmacology - 25.03.2024
Progress made in understanding Crohn’s disease
Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments. By analysing draining mesenteric lymph nodes of affected small intestinal segments of patients who had required surgery, a research team led by Lukas Unger from MedUni Vienna identified immune responses that improve our understanding of the disease.

Health - Pharmacology - 22.03.2024
Cervical cancer: immunotherapy proven to improve prognosis
Cervical cancer: immunotherapy proven to improve prognosis
Since 1999, the standard treatment for locally advanced cervical cancer has consisted of external radiotherapy followed by chemotherapy and brachytherapy. As the prognosis for patients is still poor in many cases despite these measures, intensive research is being conducted into new options. In a large-scale clinical trial, an international team involving MedUni Vienna has shown that the immunotherapeutic agent pembrolizumab in combination with chemoradiotherapy leads to a statistically significant improvement compared to chemoradiotherapy alone.

Health - Pharmacology - 15.03.2024
New insights could improve treatment of liver fibrosis
Repeated or chronic liver injury, for example by viral hepatitis or alcohol consumption, triggers a complicated molecular process of scaring called liver fibrosis. Researchers at CeMM and MedUni Vienna have now succeeded in better understanding this process in a new study by examining gene activities at various stages of the liver disease.

Health - Pharmacology - 13.03.2024
New findings on the prevention of heart attacks and strokes
New findings on the prevention of heart attacks and strokes
Blockage of arterial blood vessels caused by atherosclerosis is largely responsible for heart attacks and strokes, which are the most common causes of death worldwide. The complex mechanisms that lead to pathological changes in the arteries are not yet fully understood. An international research team led by the Medical University of Vienna and the University Hospital of Würzburg has now made important progress in understanding this disease and identified potential new approaches for early detection and therapy.

Physics - Pharmacology - 11.03.2024
Can quantum computers help in the development of new drugs?
Can quantum computers help in the development of new drugs?
Scientists predict that quantum computers will be able to discover drugs faster than conventional computers in the future Quantum computers have promising potential applications. One potential area of application is computer-aided research and development of new drugs. A team from the University of Vienna, together with researchers from Boehringer Ingelheim, BASF, Google, QC Ware and the University of Toronto, have investigated the possibilities of this technology in a review article published in the journal Nature Physics .

Pharmacology - Health - 11.03.2024
Further developed COVID vaccine from MedUni Vienna shows promising results against Omikron
Researchers at the Center for Pathophysiology, Infectiology and Immunology at the Medical University of Vienna have further developed their Covid-19 vaccine, which has now shown promise in the fight against the Omikron variant of the virus. The results of their work were recently published in the top journal "Vaccines".

Health - Pharmacology - 15.02.2024
Chronic fatigue syndrome: number of patients is expected to double due to long-term effects of the COVID-19 pandemic
Up to 80,000 people in Austria are estimated to suffer from chronic fatigue syndrome, also known as ME/CFS or myalgic encephalomyelitis/chronic fatigue syndrome. The number of ME/CFS patients is expected to rise drastically due to long-term effects of the COVID-19 pandemic. However, research in the field has neither identified mechanisms of disease onset nor causal treatment approaches.

Health - Pharmacology - 14.02.2024
New treatment option for heart valve insufficiency
Severe heart disease or pulmonary hypertension often lead to a leak in the tricuspid valve, the valve between the right atrium and the right ventricle. However, tricuspid regurgitation can also occur without a clearly identifiable cause. In the past, this leakage was mainly treated with medication using diuretics and, for some years now, with clips inserted into the heart valve.