news 2024

The results of a multicentre study on multiple sclerosis recently published in the journal "Neurology" could significantly improve the treatment of this chronic inflammatory disease. Researchers from the Medical Universities of Innsbruck and Vienna and the Inselspital, University Hospital Bern have shown that two or more lesions in the brain visible on magnetic resonance imaging (MRI) within one year are an indication in favour of intensifying treatment.

An international research group led by MedUni Vienna and IMBA - Institute of Molecular Biotechnology, Vienna, has made significant progress in understanding the mechanisms that influence the sensation of pain after surgery. Currently available treatment methods for post-operative pain can cause considerable side effects and are often only partially effective.

Sea anemone regulates stem cells through evolutionarily conserved genes The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time.

Research team identifies unconventional energy source for recently discovered "green" nitrifying bacteria An international research team led by the Centre for Microbiology and Environmental Systems Science (CeMESS) at the University of Vienna has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source.

The nuclear pore basket is a filamentous structure attached to the nucleoplasmic side of the nuclear pore complex (NPC), crucial for regulating transport between the nucleus and cytoplasm. In a paper published in Nature Cell Biology, Edvinas Stankunas and Alwin Köhler revealed the structural basis of the basket filaments and their docking mechanism to the main body of the NPC.

New practical guidelines provide an overview of senescence markers in rodent tissues, transgenic models, non-mammalian systems, human tissues and tumors and their use in the identification and specification of senescent (aging) cells. The guidelines provide a unified, modern and accessible set of tools to improve the understanding of cellular senescence in vivo.

ISTA researchers uncover how 'mortal filaments' self-assemble and maintain order A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell.

Researchers at TU Graz have published a video game about the health effects of the microbiome and what impact our lifestyle has on it. Countless microorganisms live on and in the human body - including viruses, bacteria and fungi. Together, they weigh two kilograms and are essential for our health: they support our immune system, promote digestion, protect our skin to name but a few examples.

Research team achieves breakthrough: chemical synthesis of high-density RNA microarrays now faster and more efficient An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research.

The artificial intelligence (AI) model GPT-4, known from its application in ChatGPT, shows impressive capabilities in biomedical research and can be used in many ways for simulations. A simulator developed at MedUni Vienna and based on GPT-4 shows increased accuracy in classifying the importance of genes in cancer cells, as well as in the prognosis of cancer patients.

From the bus window to the DNA laboratory: Postbuses make the diversity of flying insects in Austria visible. The University of Innsbruck is launching an innovative project to record insect biodiversity. Wipe and know which insects fly in Austria: In the new biodiversity project of the Institute of Zoology at the University of Innsbruck, public transport in Tyrol, Carinthia, Lower Austria and Upper Austria is helping to study the diversity of microorganisms.

Despite enormous progress over the past two decades, patients have not yet been able to feel a bionic prosthesis in a natural, intuitive way. Now a research team led by Oskar Aszmann from MedUni Vienna has made significant progress in sensitising the artificial extremities: By developing a new type of interface between man and machine, the feeling of the lost limb has been restored for the first time.

Newly discovered symbiosis between Rhizobia and diatoms could also open new avenues for agriculture In a new study, scientists from the Max Planck Institute for Marine Microbiology, the Alfred Wegener Institute and the University of Vienna shed light on an unexpected partnership: A marine diatom and a bacterium that can account for a large share of nitrogen fixation in vast regions of the ocean.

In a study recently published in the "British Journal of Cancer", a research team led by Mario Mikula from MedUni Vienna has shown that human skin organoids can be used to study the growth of malignant melanoma. The investigations using this instrument, which is extremely valuable for basic research, revealed that the loss of the neuronal protein NLGN4X in melanoma is associated with the progression of the disease, and that the loss of the neuronal protein NLGN4X is associated with the progression of the disease.

Looking under the microscope, a group of cells slowly moves forward in a line, like a train on the tracks. The cells navigate through complex environments. A new approach by researchers involving the Institute of Science and Technology Austria (ISTA) now shows how they do this and how they interact with each other.

A research team from TU Graz and the Czech Academy of Sciences has used two enzymes to eliminate the need for highly toxic cyanide in the production of nitriles. If the household cleaner emits a lemon-like odour, this may be due to a nitrile called citronellyl nitrile. These versatile chemical nitrile groups are also used in the manufacture of active pharmaceutical ingredients, superglue and chemical-resistant gloves.

Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment. The study was published in the renowned journal Nature Communications.

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from the so-called dentritic cells of the immune system influences their development and thus improves anti-tumor immunity.

As prostate cancer progresses, it becomes increasingly aggressive and can metastasise. In this form, the tumour is difficult to treat, which is reflected in high mortality rates: Worldwide, the malignant disease of the prostate is the second most common cause of cancer death in men. An international study led by Lukas Kenner (MedUni Vienna) and Sabine Lagger (Vetmeduni Vienna) has now identified a protein that could slow tumour growth.

New mathematical framework sheds light on how cells communicate to form embryo Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds.