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Health - Pharmacology - 16.07.2024
New approach to improve targeted skin cancer therapies
Targeted therapies are a powerful weapon against skin cancer, but their side effects can severely impact a patient's quality of life. A new study shows that some targeted therapies manipulate signaling events in cells that line blood vessels and result in a weaker vascular barrier. This knowledge sheds some light on possible mechanisms leading to side effects and it can contribute to the development of better therapies for skin cancer.

Health - Pharmacology - 15.07.2024
SARS-CoV-2 infections have a long-term impact on the immune systemg
In a study recently published in the renowned journal "Allergy", a MedUni Vienna research team shows that COVID-19 leads to considerable long-term changes in the immune system, even in mild cases. The findings could help to better understand the long-term consequences of an infection with SARS-CoV-2.

Health - 12.07.2024
Dynamic changes in the lung immune system of breast cancer metastasis
New research from the Medical University of Vienna in collaboration with Stanford University and the University of California, San Francisco, gives unprecedented insights into the dynamic remodeling of immune cells in the metastatic niche starting from early tumor development up to late-stage metastasis.

Health - Life Sciences - 11.07.2024
’ChatGPT’ for biomedical simulations
The artificial intelligence (AI) model GPT-4, known from its application in ChatGPT, shows impressive capabilities in biomedical research and can be used in many ways for simulations. A simulator developed at MedUni Vienna and based on GPT-4 shows increased accuracy in classifying the importance of genes in cancer cells, as well as in the prognosis of cancer patients.

Health - 10.07.2024
Coronary bypass grafts fail more frequently in women than in men
An international study in which MedUni Vienna played a key role has shown that women are more likely to experience bypass graft failure after coronary bypass surgery than men, which increases their risk of heart attack. The research recently published in the prestigious "Journal of the American College of Cardiology" is the most comprehensive scientific evaluation of bypass graft failure in women to date and emphasises the need for sex-specific treatment measures.

Health - Pharmacology - 09.07.2024
Active substance identified for the prevention of chlamydial infections
Despite the significant increase in sexually transmitted diseases in recent years, there is currently no vaccine available against common bacterial pathogens such as chlamydia. In the search for ways to prevent infection, a research team from MedUni Vienna and the CeMM Research Center for Molecular Medicine has identified the active substance pentamidine as a promising candidate for the prophylaxis of chlamydial infections and possibly other bacterial sexually transmitted diseases.

Health - Life Sciences - 27.06.2024
Progress in understanding metastatic melanoma
In a study recently published in the "British Journal of Cancer", a research team led by Mario Mikula from MedUni Vienna has shown that human skin organoids can be used to study the growth of malignant melanoma. The investigations using this instrument, which is extremely valuable for basic research, revealed that the loss of the neuronal protein NLGN4X in melanoma is associated with the progression of the disease, and that the loss of the neuronal protein NLGN4X is associated with the progression of the disease.

Health - Pharmacology - 27.06.2024
Non-invasive tests for liver health
Non-invasive tests for liver health
Advanced liver disease is the second most common cause of lost working years, as it disproportionately affects young patients. A scientific team from MedUni Vienna has been able to determine a threshold value for a simple blood test that can be used to identify people with an increased risk of complications, even without special testing.

Health - 19.06.2024
Gestational diabetes: Newly identified subgroups improve personalised therapy
Patients with gestational diabetes show different disease progressions and therefore require personalised treatment measures. An international research team led by MedUni Vienna has now identified three subgroups of the disease with different treatment needs. The results of the study, recently published in the prestigious journal "Diabetologia", could improve our understanding of gestational diabetes and significantly advance the development of personalised treatment concepts.

Health - Life Sciences - 11.06.2024
New insights on polymicrobial infections in chronic lung diseases
Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment. The study was published in the renowned journal Nature Communications.

Health - Life Sciences - 07.06.2024
Inhibition of epigenetic control enzymes in immune cells as a potential new starting point in cancer immunotherapy
Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from the so-called dentritic cells of the immune system influences their development and thus improves anti-tumor immunity.

Health - Life Sciences - 05.06.2024
Prostate cancer: Protein identified to reduce tumour growth
As prostate cancer progresses, it becomes increasingly aggressive and can metastasise. In this form, the tumour is difficult to treat, which is reflected in high mortality rates: Worldwide, the malignant disease of the prostate is the second most common cause of cancer death in men. An international study led by Lukas Kenner (MedUni Vienna) and Sabine Lagger (Vetmeduni Vienna) has now identified a protein that could slow tumour growth.

Health - Pharmacology - 04.06.2024
Heart: New heart valve prosthesis enables broader applicability
A catheter-based tricuspid valve replacement with a newly approved heart valve was performed for the first time in Austria at University Hospital Vienna and MedUni Vienna. The new heart valve prosthesis now also makes it possible to treat patients who could previously only be treated with medication for anatomical reasons or due to the cause of the heart valve leak.

Health - Pharmacology - 03.06.2024
New findings on the prevention of rejection reactions in organ transplants
Immunosuppressive drugs protect transplanted organs from harmful immune reactions. Nevertheless, rejection reactions can still occur. A MedUni Vienna research team led by Thomas Wekerle has deciphered mechanisms that lead to rejection despite the use of the latest immunosuppressive drugs. These findings point to new therapeutic options for preventing such rejection reactions in the future.

Pharmacology - Health - 27.05.2024
New therapy proven effective against rejection in kidney transplantation
New therapy proven effective against rejection in kidney transplantation
Antibody-mediated rejection (AMR) is one of the most common causes of kidney transplant failure. To date, however, no treatment has proven effective in combating this complication in the long term. As part of an international and multidisciplinary clinical study led by Georg Böhmig and Katharina Mayer, Clinical Division of Nephrology and Dialysis, Department of Medicine III at MedUni Vienna and University Hospital Vienna, a new therapeutic principle in transplant medicine has been found to be both safe and highly effective.

Physics - Health - 13.05.2024
New method unravels the mystery of slow electrons
New method unravels the mystery of slow electrons
Slow electrons are used in cancer therapy as well as in microelectronics. It is very hard to observe how they behave in solids. But scientists at TU Wien have made this possible. Electrons can behave very differently depending on how much energy they have. Whether you shoot an electron with high or low energy into a solid body determines which effects can be triggered.

Health - Pharmacology - 13.05.2024
Limited efficacy of common local anaesthetic
Liposomal bupivacaine was launched on the market twelve years ago to provide long-lasting local control of pain. The medication is used as a local anaesthetic, particularly for orthopaedic operations. A research study by MedUni Vienna has now shown the limited effectiveness of the substance. The study has just been published in the journal "Anesthesiology", the peer-reviewed journal of the American Society of Anesthesiologists (ASA).

Health - 08.05.2024
Frequent salting of food increases the risk of stomach cancer
In Asian countries, where high-salt foods are popular, the link between high salt consumption and stomach cancer has already been proven. A long-term study by MedUni Vienna has now shown for the first time that this risk is also reflected in the cancer statistics in Europe. As the analysis recently published in the specialist journal "Gastric Cancer" shows, people who frequently add salt to their food are around 40 per cent more likely to develop stomach cancer than those who do not use the salt shaker at the table.

Health - Pharmacology - 02.05.2024
Immunotherapy for lung cancer effective even before surgery
Blocking "switches" of the immune system has revolutionized the treatment of patients with various metastatic cancers. In 2018, the discovery of this principle was recognized by the Nobel Prize in Medicine. An international research team has now shown that the simultaneous inhibition of two "immune switches", PD-1 and LAG-3, can lead to the killing of lung cancer cells after just a few weeks.

Health - 02.05.2024
Underestimated risk of lung transplantation researched
Underestimated risk of lung transplantation researched
PLS (Passenger Lymphocyte Syndrome) is a potentially life-threatening risk in lung transplants that has hardly been researched and is often underestimated in clinical practice. However, the complication occurs more frequently than previously thought, as shown by a recent study at the Department of Transfusion Medicine and Cell Therapy in collaboration with the Department of Thoracic Surgery at MedUni Vienna and University Hospital Vienna.
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