Medicine and Life Sciences - Pharmacology
A study from the University of Vienna shows a positive effect of vaccination even in patients requiring oxygen. Previous studies have shown that the mortality rate of Corona patients hospitalized and requiring oxygen therapy is similar no matter if they are vaccinated or unvaccinated. An international research team led by David Gómez-Varela from the Department for Pharmaceutical Sciences at the University of Vienna has now disproved these findings in a comprehensive multicontinental analysis
A recent study involving MedUni Vienna and University Hospital Vienna has identified a significant advance in the treatment of chronic lymphocytic leukaemia (CLL). The results of the randomised Phase III CLL13 (GAIA) study show that a time-limited and targeted therapy with venetoclax and obinutuzumab is more effective than chemoimmunotherapy in patients without comorbidities. The findings have the potential to revolutionize the standard of care for CLL patients and offer them a better quality of life. The study was published in the prestigious journal The New England Journal of Medicine.
A global study led by Gerald Prager of the Department of Medicine I and the Comprehensive Cancer Center (CCC) Vienna, a joint MedUni Vienna and University Hospital Vienna facility, and co-workers has demonstrated that the prognosis for patients with metastatic colorectal cancer can be significantly improved. The new treatment standard, comprising a combination of targeted treatment and oral chemotherapy, is expected to start benefiting Austrian patients very soon. The study has just been published in the New England Journal of Medicine.
Common Variable Immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency in humans. Patients suffer from recurrent infections of the upper and lower respiratory tract but many of them also develop more severe symptoms such as granulomas, lymphomas and autoimmune diseases. An international team of researchers led by MedUni Vienna has now discovered why some CVID patients develop an autoimmune disease and others do not. The results of the study were published in the journal Cell Reports.
Faecal incontinence is a major taboo subject and, if left untreated, usually restricts the quality of life of those severely affected. Under the leadership of surgeon Stefan Riss from the Department of General Surgery at MedUni Vienna and the University Hospital Vienna, a study has been launched into a new surgical treatment method. A new anal band is being tested, which should seal the anus better than previous methods and enable long term controlled bowel movements.
