Medicine and Life Sciences - Pharmacology
Chemists in Vienna find a method to replace hydrogen with fluorine in organic molecules The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease.
The research group of Nuno Maulide from the Faculty of Chemistry of the University of Vienna has, in cooperation with the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, achieved the synthesis of a potential immunosuppressive agent by modification of a naturally occurring compound. In this endeavour, the researchers have employed a masking trick to "hide" a reactive species inside the target molecule. The results were recently published in the renowned "Journal of the American Chemical Society".